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amarogentin

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Origin: China

Cas No: 21018-84-8

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

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CAS No.: 21018-84-8 Formula: C29H30O13 Molecular Weight: 586.54100

Description

Amarogentin is a chemical compound found in gentian (Gentiana lutea) or in Swertia chirata.
Amarogentin and gentiopicrin, the bitter glycosides from gentian root; Gentian root has a long history of use as a herbal bitter in the treatment of digestive disorders and is an ingredient of many proprietary medicines. The bitter principles of gentian root are secoiridoid glycosides amarogentin and gentiopicrin. The former is one of the most bitter natural compounds known and is used as a scientific basis for measuring bitterness. In humans, it activates the bitter taste receptor hTAS2R50. The biphenylcarboxylic acid moiety is biosynthesized by a polyketide-type pathway, with three units of acetyl-CoA and one unit of 3-hydroxybenzoyl-CoA, this being formed from an early shikimate pathway intermediate and not via cinnamic or benzoic acid.
It also shows an antileishmanial activity in animal models being an inhibitor of topoisomerase I.

Basic Info

Chemical Name	amarogentin
Synonyms	amorogentin; AMAROGENTIN; sweroside-2'-O-3",5",3'''-trihydroxy-biphenyl-2''-carboxylic acid; amarosgentin; Amarogentin Hydrate;
CAS No.	21018-84-8
Molecular Formula	C29H30O13
Molecular Weight	586.54100
PSA	201.67000
LogP	1.05690