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Tetramethylpyrazine

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Origin: China

Cas No: 1124-11-4

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Quick Details
CAS No.:
1124-11-4
Other Names:
Tetramethylpyrazine
MF:
C8H12N2
EINECS No.:
214-391-2
FEMA No.:
1234
Place of Origin:
Henan, China
Type:
Natural Flavour & Fragrances
Usage:
Daily Flavor, Food Flavor, Industrial Flavor, Tobacco Flavor
Purity:
99%
Natural Variety:
Plant Extract
Brand Name:
tianfu
Model Number:
123
shelf life:
2 years
Packaging&Delivery
Packaging Details
In aluminum bottles, net weight 1 or 5 or 10 kilos, or in PVF inner steel drums, net weight 25 or 50 kilos
Port
Any port in China
Lead Time:
within 15 days after the orde rconfirmed

Property

CAS No.: 1124-11-4 Formula: C8H12N2 Molecular Weight: 136.19400

Description

Tetramethylpyrazine, also known as ligustrazine, is an antiinflammatory compound isolated from the fermented food natto. It demonstrated in vivo nootropic activity in rats.

Basic Info

Chemical Name	Tetramethylpyrazine
Synonyms	Pyrazine, tetramethyl-; 2,3,5,6-tetramethylpyrazine;
CAS No.	1124-11-4
Molecular Formula	C8H12N2
Molecular Weight	136.19400
PSA	25.78000
LogP	1.71020

Properties

Appearance & Physical State	white crystals or powder
Density	1.08
Boiling Point	190ºC
Melting Point	82-86ºC
Flash Point	128-130°C/200mm
Refractive Index	1.503
Stability	Stable. Incompatible with strong acids, strong oxidizing agents.
Storage Condition	Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Vapor Pressure	0.671mmHg at 25°C

Safety Info

RTECS	UQ3905000
Safety Statements	S24/25
HS Code	29339990
WGK Germany	3
Risk Statements	R22
Hazard Codes	Xn
Signal Word	Danger
Hazard Declaration	H302; H315; H318; H335
Symbol	GHS05, GHS07
Caution Statement	P261; P280; P305 + P351 + P338

Synthesis Route

2-[2-Hydroxy-2-(p-nitrophenyl)ethyl]-3,5,6-trimethylpyrazine→Tetramethylpyrazine+4-nitrobenzaldehyde
3-hydroxy-4-hydroxyimino-valeric acid→Tetramethylpyrazine+carbon dioxide
2-[2-Hydroxy-2-[p-(dimethylamino)phenyl]ethyl]-3,5,6-trimethylpyrazine→Tetramethylpyrazine+4-Dimethylaminobenzaldehyde

Precursor

2,5-DICHLORO-3,6-DIMETHYLPYRAZINE
3-aminobutan-2-one hydrochloride
acetoin
Trimethylaluminium

Downstream Product

Pyrazine, tetramethyl-, 1-oxide (8CI,9CI)
3,5,6-trimethylpyrazine-2-carboxylic acid
2,3,5,6-tetramethyl-4-oxidopyrazin-1-ium 1-oxide
2,3,5-trimethyl-6-(prop-2-enylsulfonylmethyl)pyrazine

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