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poly(I:C)

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Origin: China

Cas No: 24939-03-5

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

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CAS No.: 24939-03-5 Formula: C19H27N7O16P2 Molecular Weight: 671.40300

Description

Polyinosinic:polycytidylic acid (usually abbreviated poly I:C) is an immunostimulant. It is used in the form of its sodium salt to simulate viral infections.
Poly I:C is known to interact with toll-like receptor 3 (TLR3), which is expressed in the membrane of B-cells, macrophages and dendritic cells. Poly I:C is structurally similar to double-stranded RNA, which is present in some viruses and is a "natural" stimulant of TLR3. Thus, Poly I:C can be considered a synthetic analog of double-stranded RNA and is a common tool for scientific research on the immune system.

Basic Info

Chemical Name	poly(I:C)
Synonyms	Polyinosinicacid-polycytidylicacid; Polyinosinic–polycytidylic acid; polyri:polyrc; polyi:c; Poly(I).Poly(C); polycpolyi; 5'-Inosinic acid homopolymer-5'-cytidylic acid homopolymer complex (1_1); Polyinosinic;
CAS No.	24939-03-5
Molecular Formula	C19H27N7O16P2
Molecular Weight	671.40300
PSA	377.00000
LogP	-4.01670