Home > All categories> Biochemicals and Pharmaceutical Chemicals> Active Pharmaceutical Ingredients (APIs)> Endocrine system> (5S,8S,9S,10S,11S,13S,14S,17S)-11-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one

(5S,8S,9S,10S,11S,13S,14S,17S)-11-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one

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Origin: China

Cas No: 298-25-9

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 298-25-9 Formula: C21H32O4 Molecular Weight: 348.47600

Description

5α-Dihydrocorticosterone ((5α,11β)-11,21-dihydroxypregnane-3,20-dione; abbreviated as 5α-DHC, 5α-DHB) is a naturally-occurring, endogenous glucocorticoid steroid hormone and neurosteroid. It is biosynthesized from corticosterone by the enzyme 5α-reductase. DHC has central depressant effects and impairs long-term potentiation in animals.

Basic Info

Chemical Name	(5S,8S,9S,10S,11S,13S,14S,17S)-11-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one
Synonyms	5-Dihydrocorticosterone; 5\|A-Dihydrocorticosterone; 5alpha-Dihydrocorticosterone; 5beta-Dihydrocorticosterone; 5\|A-Pregnane-11\|A,21-diol-3,20-dione;
CAS No.	298-25-9
Molecular Formula	C21H32O4
Molecular Weight	348.47600
PSA	74.60000
LogP	2.74660

Properties

Density	1.175 g/cm3
Boiling Point	508.5ºC at 760 mmHg
Flash Point	275.4ºC
Refractive Index	1.548
Vapor Pressure	1.82E-12mmHg at 25°C

Synthesis Route

Corticosterone 21-Acetate→corticosterone+(5S,8S,9S,10S,11S,13S,14S,17S)-11-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one
corticosterone→(5S,8S,9S,10S,11S,13S,14S,17S)-11-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one
Corticosterone 21-Acetate→(5S,8S,9S,10S,11S,13S,14S,17S)-11-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one

Precursor

Ethanol
Corticosterone 21-Acetate
corticosterone

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