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5-HYDROXY-2'-DEOXYCYTIDINE

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Origin: China

Cas No: 52278-77-0

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

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CAS No.: 52278-77-0 Formula: C9H13N3O5 Molecular Weight: 243.21700

Description

5-Hydroxy-2’-deoxycytidine have been used as a substrate for uracil DNA N-glycosylase and has been used to study the oxidation of DNA due to exposure to reactive oxygen species.

Basic Info

Chemical Name	5-HYDROXY-2'-DEOXYCYTIDINE
Synonyms	5-Ohdc; 5-hydroxydeoxycytidine; 5-Hydroxy-2`-deoxycytidine;
CAS No.	52278-77-0
Molecular Formula	C9H13N3O5
Molecular Weight	243.21700
PSA	130.83000
LogP	-1.24700

Properties

Density	1.89g/cm3
Boiling Point	536.1ºC at 760mmHg
Flash Point	278ºC
Refractive Index	1.756

Synthesis Route

2'-deoxycytidine→5-HYDROXY-2'-DEOXYCYTIDINE
4-Amino-5-bromo-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one→5-HYDROXY-2'-DEOXYCYTIDINE
2'-deoxycytidine→4-Amino-5-bromo-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one+5-HYDROXY-2'-DEOXYCYTIDINE

Precursor

4-Amino-5-bromo-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one
2'-Deoxycytidine hydrochloride
2'-deoxycytidine

Downstream Product

6-amino-5-hydroxy-1H-pyrimidin-2-one

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