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3-(Dimethylamino)-1-phenyl-1-propanol

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Origin: China

Cas No: 5554-64-3

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

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CAS No.: 5554-64-3 Formula: C11H17NO Molecular Weight: 179.25900

Description

3-Dimethylamino-1-phenyl-1-propanol is a useful synthetic intermediate. It can be used to prepare phenoxyphenyl diamine-based histamine H3 antagonists with serotonin reuptake inhibitor activities. It is also used to synthesize indolyl aryl propanamines as dual acting norepinephrine and serotonin reuptake inhibitors.

Basic Info

Chemical Name	3-(Dimethylamino)-1-phenyl-1-propanol
Synonyms	2-(1,1-Dimethyl-2-propenyl)-3-hydroxy-1,4-naphthalenedione; 2-hydroxy-3-(1,1-dimethylallyl)-1,4-naphthoquinone; 3-(dimethylamino)-1-phenyl-propan-1-ol; 2-(1,1-dimethyl-2-propenyl)-3-hydroxy-1,4-naphthoquinone; 3-(Dimethylallyl)-2-hydroxy-1,4-naphthoquinone; N,N-dimethyl-3-phenyl-3-hydroxy-propanamine; (+/-)-dimethyl(3-hydroxy-3-phenylpropyl)amine; 3-dimethylamino-1-phenyl-1-propanol; 2-(1,1-dimethylprop-2-enyl)-3-hydroxy-1,4-naphthoquinone; N,N-Dimethyl-3-hydroxy-3-phenylpropylamine; 2-(1,1-dimethylprop-2-enyl)-3-hydroxy-naphthalene-1.4-dione;
CAS No.	5554-64-3
Molecular Formula	C11H17NO
Molecular Weight	179.25900
PSA	23.47000
LogP	1.67170

Properties

Density	1.011g/cm3
Boiling Point	284.4ºC at 760mmHg
Flash Point	99.8ºC

Safety Info

HS Code	2922199090

Synthesis Route

phenylene-ethylene+N-(chloromethyl)dimethylamine→2-benzylprop-2-enal+3-(Dimethylamino)-1-phenyl-1-propanol
3-(DIMETHYLAMINO)-1-PHENYLPROPAN-1-ONE→3-(Dimethylamino)-1-phenyl-1-propanol
3-Dimethylaminopropiophenone hydrochloride→3-(Dimethylamino)-1-phenyl-1-propanol

Precursor

3-Dimethylaminopropiophenone hydrochloride
N,N-Dimethyl-α-chlorobenzoylacetamide
acetophenone

Downstream Product

3-(dimethylamino)-1-phenylpropan-1-ol,hydrochloride
3-chloro-N,N-dimethyl-3-phenylpropan-1-amine,hydrochloride
N,N-dimethyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine

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