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raloxifene hydrochloride

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Origin: China

Cas No: 82640-04-8

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 82640-04-8 Formula: C28H28ClNO4S Molecular Weight: 510.04400

    Description

    A nonsteroidal, selective estrogen receptor modulator (SERM). Antiosteoporotic. Insoluble in water.

    Basic Info

    Chemical Name raloxifene hydrochloride
    Synonyms

    Raloxifene Hydrochloride;

    CAS No. 82640-04-8
    Molecular Formula C28H28ClNO4S
    Molecular Weight 510.04400
    PSA 98.24000
    LogP 6.81510

    Properties

    Appearance & Physical State Light yellow solid
    Density 1.285g/cm3
    Boiling Point 728.2ºC at 760 mmHg
    Melting Point 143-147ºC
    Flash Point 394.2ºC
    Refractive Index 1.654
    Storage Condition -20ºC Freezer

    Safety Info

    Safety Statements S22; S24/25
    Risk Statements R36/37/38
    Hazard Codes Xi

    Synthesis Route

    [4-(6-acetyloxy-1-benzothiophen-2-yl)phenyl] acetate+4-[2-(1-Pipiridine)ethoxybenzoic acid hydrochloride→raloxifene hydrochloride
    [6-Methoxy-2-(4-methoxyphenyl)-1-benzothiophen-3-yl]{4-[2-(1-pipe ridinyl)ethoxy]phenyl}methanone hydrochloride (1:1)→raloxifene hydrochloride
    6-Methoxy-2-(4-methoxyphenyl)benzo[b]thiophene+4-[2-(1-Pipiridine)ethoxybenzoic acid hydrochloride→raloxifene hydrochloride

    Precursor

    4-[2-(1-Pipiridine)ethoxybenzoic acid hydrochloride
    [6-[(methylsulfonyl)oxy]-2-[4-[(methylsulfonyl)oxy]phenyl]benzo[b]thien-3-yl][4-[2-(1-pyrrolidinyl)ethoxy]phenyl]methanone hydrochloride
    [4-(6-acetyloxy-1-benzothiophen-2-yl)phenyl] acetate
    [6-Methoxy-2-(4-methoxyphenyl)-1-benzothiophen-3-yl]{4-[2-(1-pipe ridinyl)ethoxy]phenyl}methanone hydrochloride (1:1)

    Downstream Product

    raloxifene

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