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(R)-pantolactone

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Origin: China

Cas No: 599-04-2

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

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CAS No.: 599-04-2 Formula: C6H10O3 Molecular Weight: 130.14200

Description

An important intermediate in the synthesis of pantothenic acid as well as a degradation product of pantothneic acid in the liver. Causes disorientation and hypothermia, and prevents phenamine-induced hyperthermia.

Basic Info

Chemical Name	(R)-pantolactone
Synonyms	D-(-)-PANTOLACTONE; (3R)-3-hydroxy-4,4-dimethyloxolan-2-one; 2(3H)-Furanone, dihydro-3-hydroxy-4,4-dimethyl-, (R)-;
CAS No.	599-04-2
Molecular Formula	C6H10O3
Molecular Weight	130.14200
PSA	46.53000
LogP	-0.06970

Properties

Appearance & Physical State	White crystalline powder or crystals
Density	1.165g/cm3
Boiling Point	120-122ºC15 mm Hg(lit.)
Melting Point	91ºC(lit.)
Flash Point	99ºC
Refractive Index	-50.8 ° (C=2, H2O)
Storage Condition	2-8ºC

Safety Info

Safety Statements	S22-S24/25
HS Code	2932209090
WGK Germany	1

Synthesis Route

methyl phenylglyoxalate+2-dehydropantolactone→(S)-(+)-Methyl mandelate+methyl (2R)-2-hydroxy-2-phenylacetate
Ethyl pyruvate+2-dehydropantolactone→ethyl (2S)-lactate+ethyl (2R)-2-hydroxypropanoate
2-dehydropantolactone→(R)-pantolactone

Precursor

(R)-2,4-dihydroxy-N-[(1R)-2-endo-hydroxy-3-endo-bornyl]-3,3-dimethylbutyramide
ethyl glyoxylate
isobutyraldehyde
2-dehydropantolactone

Downstream Product

Dexpanthenol
(R)-pantothenic acid
(2R)-2,4-dihydroxy-N-[3-(2-hydroxyethylamino)-3-oxopropyl]-3,3-dimethylbutanamide
Sulfopantothenic acid

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