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N,O-bis(trimethylsilyl)trifluoroacetamide

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Origin: China

Cas No: 25561-30-2

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Product Description

Quick Details
CAS No.:
25561-30-2
Other Names:
N,O-Bis(trimethylsily)trifluoroamide
MF:
C8H18F3NOSi2
EINECS No.:
247-103-9
Place of Origin:
Jiangsu, China
Type:
Syntheses Material Intermediates
Purity:
>99%
Brand Name:
KPRX
Model Number:
CAS 25561-30-2
Application:
Organic synthesis
Appearance:
Colorless to pale yellow liquid
Product name:
High quality 25561-30-2 with fast delivery
Usage:
Used for synthesis of pharmaceutical intermediates.
Name:
Bis(trimethylsilyl)trifluoroacetamide
Apperance:
Colorless to pale yellow liquid
Description:
Silicon Compounds for Synthesis
Packaging&Delivery
Packaging Details
20kg/carton
Pallet can be avialable for bulk order.
Port
Shanghai any port of China
Lead Time:
Quantity(Kilograms) 1 - 1000 >1000
Est. Time(days) 15 To be negotiated

Property

CAS No.: 25561-30-2 Formula: C8H18F3NOSi2 Molecular Weight: 257.40100

Description

N,O-Bis(trimethylsilyl)trifluoroacetamide (BSTFA) is a chemical compound that is used to derivatise labile groups such as hydroxyl on other chemicals, with the more stable trimethylsilyl group, which protects the labile group and allows the compound to be used for analytical purposes or as a chemical reagent for synthesis of more complex molecules. Siloxanes are usually more volatile than the corresponding hydroxyl compounds, and thus can be analyzed with gas chromatography better than the parent compound.

Basic Info

Chemical Name	N,O-bis(trimethylsilyl)trifluoroacetamide
Synonyms	N,O-bis-TMS-trifluoroacetamide; Bis(trimethylsilyl)trifluoroacetamide; 8 Reaction vial,capacity; Bis(trimethylsilyl); N,O-BSTFA; REGISIL(R) RC-1; bstfa kit; BSTFA; N,O-Bis(trimethylsilyl)trifluoroacetamide Kit BSTFA 1 mL × REGISIL RC-3; REGISIL RC-2; REGISIL RC-1; bstfa + tmcs;
CAS No.	25561-30-2
Molecular Formula	C8H18F3NOSi2
Molecular Weight	257.40100
PSA	21.59000
LogP	3.63360

Properties

Appearance & Physical State	Clear to yellowish clear liquid
Density	0.96
Boiling Point	142ºC
Melting Point	-10ºC
Flash Point	23ºC
Refractive Index	1.3829-1.3849
Water Solubility	hydrolyses
Stability	Stable under normal temperatures and pressures.
Storage Condition	2-8ºC
Vapor Pressure	0.193mmHg at 25°C

Safety Info

Hazard Class	3
Safety Statements	S16-S26-S36/37/39-S45
HS Code	29310095
Packing Group	III
WGK Germany	3
RIDADR	UN 2924 3/PG 3
Risk Statements	R10; R34
Hazard Codes	C
Caution Statement	P210; P280; P305 + P351 + P338; P310
Signal Word	Danger
Supplemental Hazard Statements	Corrosive to the respiratory tract; Reacts violently with water.
Symbol	GHS02, GHS05, GHS07
Hazard Declaration	H225; H302; H314

Synthesis Route

chlorotrimethylsilane+2,2,2-trifluoroacetamide→N,O-bis(trimethylsilyl)trifluoroacetamide
trifluoroacetyl chloride+Sodium bis(trimethylsilyl)amide→N,O-bis(trimethylsilyl)trifluoroacetamide

Precursor

2,2,2-trifluoroacetamide
trifluoroacetyl chloride
Sodium bis(trimethylsilyl)amide
chlorotrimethylsilane

Downstream Product

3,4-bis(trimethylsilyloxy)benzaldehyde
bis(trimethylsilyl) undecanedioate
(3-λ<sup>1</sup>-silanyloxy-5-trimethylsilyloxyphenoxy)silicon
5-fluoro-N-trimethylsilyl-2-trimethylsilyloxypyrimidin-4-amine

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