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Home > Chiral Compounds> Methyl 2-(S)-[N-Carbobenzyloxy]amino-3-aminopropionate, Hydrochloride
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Methyl 2-(S)-[N-Carbobenzyloxy]amino-3-aminopropionate, Hydrochloride

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Origin: China

Cas No: 35761-27-4

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 35761-27-4 Formula: C12H17ClN2O4 Molecular Weight: 288.72700

    Description

    Important building block for the synthesis of peptides containing DAP residues, e.g. bleomycins, edeines, tuberactinomycins.

    Basic Info

    Chemical Name Methyl 2-(S)-[N-Carbobenzyloxy]amino-3-aminopropionate, Hydrochloride
    Synonyms

    methyl (2S)-3-amino-2-(phenylmethoxycarbonylamino)propanoate,hydrochloride;

    CAS No. 35761-27-4
    Molecular Formula C12H17ClN2O4
    Molecular Weight 288.72700
    PSA 90.65000
    LogP 2.30630

    Properties

    Density 1.212g/cm3
    Boiling Point 423.692ºC at 760 mmHg
    Melting Point 157-162ºC dec.
    Flash Point 210.042ºC
    Refractive Index 1.537

    Synthesis Route

    Nα-Cbz-β-amino-L-alanine methyl ester→Methyl 2-(S)-[N-Carbobenzyloxy]amino-3-aminopropionate, Hydrochloride
    Methanol+(S)-3-Amino-2-(benzyloxycarbonylamino)-propanoic acid→Methyl 2-(S)-[N-Carbobenzyloxy]amino-3-aminopropionate, Hydrochloride
    methyl (2S)-3-[(2-methylpropan-2-yl)oxycarbonylamino]-2-(phenylmethoxycarbonylamino)propanoate→Methyl 2-(S)-[N-Carbobenzyloxy]amino-3-aminopropionate, Hydrochloride

    Precursor

    Nα-Cbz-β-amino-L-alanine methyl ester
    (S)-3-Amino-2-(benzyloxycarbonylamino)-propanoic acid
    (2S)-4-amino-4-oxo-2-(phenylmethoxycarbonylamino)butanoic acid
    Methanol

    Downstream Product

    methyl 3-(methylamino)-2-(phenylmethoxycarbonylamino)propanoate
    methyl (2S)-3-[(2-methylpropan-2-yl)oxycarbonylamino]-2-(phenylmethoxycarbonylamino)propanoate

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