Home > All categories> Biochemicals and Pharmaceutical Chemicals> Pharmaceutical Impurities> iohexol

iohexol

Get Latest Price >

FOB Price contact us for price

Origin: China

Cas No: 66108-95-0

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

Vendor:

Payment Terms:

Inquiry now

* Send an Inquiry to us

Add to wishlist

* Name your price
* Start order doesn't mean buying now

Products Specification
Product Description

Property

CAS No.: 66108-95-0 Formula: C19H26I3N3O9 Molecular Weight: 821.13800

Description

Iohexol is a contrast agent, sold under the trade names Omnipaque and Exypaque; this compound is also sold as a density gradient medium under the names Accudenz, Histodenz and Nycodenz. It is available in various concentrations, from 140 to 350 milligrams of iodine per milliliter. Omnipaque 350 is commonly used as a contrast agent during coronary angiography.
The osmolality of iohexol ranges from 322 mOsm/kg—approximately 1.1 times that of blood plasma—to 844 mOsm/kg, almost three times that of blood. Despite this difference, iohexol is still considered a low-osmolality contrast agent; the osmolality of older agents, such as diatrizoate, may be more than twice as high.

Basic Info

Chemical Name	iohexol
Synonyms	omnipaqueTM; Exypaque; 5-[acetyl(2,3-dihydroxypropyl)amino]-1-N,3-N-bis(2,3-dihydroxypropyl)-2,4,6-triiodobenzene-1,3-dicarboxamide; Omnipaque; EINECS 266-164-2; Omnipaque 240; Iohexolum; Nycodenz;
CAS No.	66108-95-0
Molecular Formula	C19H26I3N3O9
Molecular Weight	821.13800
PSA	199.89000
LogP	-0.84570

Properties

Appearance & Physical State	white powder
Density	2.2 g/cm3
Boiling Point	891.5ºC at 760 mmHg
Melting Point	254-256ºC
Flash Point	493ºC
Refractive Index	1.724
Stability	Stable at normal temperatures and pressures.
Storage Condition	-20ºC

Safety Info

RTECS	CZ2205000
Safety Statements	S22-S24/25
HS Code	2924299090
WGK Germany	1

Synthesis Route

5-(Acetamido)-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzenedicarboxamide+epichlorohydrin→iohexol+iodixanol
5-(Acetamido)-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzenedicarboxamide→iohexol+iodixanol
5-(Acetamido)-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzenedicarboxamide+3-chloropropane-1,2-diol→iohexol

Precursor

n-Butanol
epichlorohydrin
5-(Acetamido)-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzenedicarboxamide
3-chloropropane-1,2-diol

Downstream Product

5-(Acetamido)-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzenedicarboxamide

Hot tags: iohexol, China, manufacturers, suppliers, factory, wholesale, low price, high quality