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Home > Aromatic Compounds> Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate
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Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate

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Origin: China

Cas No: 128625-52-5

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Quick Details

    CAS No.:
    128625-52-5
    Other Names:
    PyBOP
    MF:
    C18H28N6OP.PF6
    EINECS No.:
    128625-52-5
    Place of Origin:
    Shandong, China
    Type:
    Agrochemical Intermediates, Dyestuff Intermediates, Flavor & Fragrance Intermediates, Pharmaceutical Intermediates, Syntheses Material Intermediates
    Purity:
    ≥98%
    Brand Name:
    Finerchem
    Model Number:
    128625-52-5
    Application:
    Pharmaceutical Intermediates
    Appearance:
    White crystalline powder
    Product name:
    Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate
    Molecular Weight:
    520.40

    Packaging&Delivery

    Packaging Details
    Aluminum foil bag for within 10kg
    Fiber drum for 10kg and more
    Port
    SHANGHAI, BEIJING, QINGDAO, SHENZHEN
    Lead Time:
    Quantity(Kilograms)1 - 10>10
    Est. Time(days)2To be negotiated

  • Property

    CAS No.: 128625-52-5 Formula: C18H28F6N6OP2 Molecular Weight: 520.39200

    Description

    PyBOP (benzotriazol-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate) is a peptide coupling reagent used in solid phase peptide synthesis. It is used as a substitute for the BOP reagent, thus avoiding the formation of the carcinogenic side product HMPA.

    Basic Info

    Chemical Name Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate
    Synonyms

    1H-Benzotriazol-1-yloxytripyrrolidinophosphonium Hexafluorophosphate;
    Benzotriazol-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate;
    (Benzotriazol-1-yloxy)tripyrrolidinophosphonium Hexafluorophosph;
    ((1H-Benzo[d][1,2,3]triazol-1-yl)oxy)tri(pyrrolidin-1-yl)phosphonium hexafluorophosphate(V);
    (Benzotriazol-1-yloxy)tripyrrolidinophosphonium Hexafluorophosphate;
    benzotriazol-1-yloxy(tripyrrolidin-1-yl)phosphanium,hexafluorophosphate;

    CAS No. 128625-52-5
    Molecular Formula C18H28F6N6OP2
    Molecular Weight 520.39200
    PSA 76.84000
    LogP 6.02100

    Properties

    Appearance & Physical State White crystalline powder
    Melting Point 160-162ºC
    Storage Condition 2-8ºC

    Safety Info

    Safety Statements S24/25
    WGK Germany 3
    RIDADR UN 1325 4.1/PG 2
    Risk Statements R36/37/38
    Hazard Codes Xi
    Signal Word Warning
    Symbol GHS07
    Hazard Declaration H315; H319; H335
    Caution Statement P261; P305 + P351 + P338

    Synthesis Route

    Tris(Pyrrolidinophosphine) Oxide+1-Hydroxybenzotriazole→Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate

    Precursor

    1-Hydroxybenzotriazole
    Tris(Pyrrolidinophosphine) Oxide

    Downstream Product

    5-bromo-2-[4-(2-hydroxy-ethyl)-piperazin-1-yl]-N,N-dimethyl-nicotinamide
    Bromotri(1-Pyrrolidinyl)Phosphonium Hexafluorophosphate
    Tris(Pyrrolidinophosphine) Oxide
    tert-butyl 3-[methoxy(methyl)carbamoyl]piperidine-1-carboxylate

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