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4-(Trifluoromethoxy)aniline

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Origin: China

Cas No: 461-82-5

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Quick Details

    CAS No.:
    461-82-5
    Other Names:
    4- threedifluoro Methoxyaniline
    MF:
    C7H6F3NO
    EINECS No.:
    207-317-5
    Place of Origin:
    Jiangsu, China
    Type:
    Agrochemical Intermediates, Pharmaceutical Intermediates, Syntheses Material Intermediates
    Purity:
    >99%
    Brand Name:
    KPRX
    Model Number:
    CAS 461-82-5
    Application:
    Organic synthesis
    Appearance:
    Clear colorless liquid
    Product name:
    Manufacturers selling 4-Trifluoromethoxyaniline 461-82-5
    Usage:
    Agrochemical & Pharmaceutical Intermediates
    Name:
    4-(Trifluoromethoxy)aniline
    Apperance:
    Clear colorless liquid
    Keyword:
    synthesis of fluorine-containing medicine, pesticide intermediates
    Description:
    intermediate of insecticide

    Packaging&Delivery

    Packaging Details
    20kg/carton
    Pallet can be avialable for bulk order.
    Port
    Shanghai any port of China
    Lead Time:
    Quantity(Kilograms)1 - 1000>1000
    Est. Time(days)15To be negotiated

  • Property

    CAS No.: 461-82-5 Formula: C7H6F3NO Molecular Weight: 177.12400

    Description

    4-(Trifluoromethoxy)aniline is used in the synthesis of anticancer agents and antitumor medicaments. Also, its an intermediate in the production of labelled Riluzole, a neuroprotective agent. Modulates glutamatergic transmission. A glutamate release inhibitor. An anticonvulsant.

    Basic Info

    Chemical Name 4-(Trifluoromethoxy)aniline
    Synonyms

    4-aminophenyl trifluoromethyl ether;
    4-TRIFLUORO METHOXYLAMINE;
    4-(trifluoromethoxy)benzeneamine;
    4-Trifluoromethoxyaniline;
    4-trifluoromethoxy-aniline;
    Riluzole Related Compound A;
    4-trifluoromethoxyaniune;
    p-Trifluoromethoxyaniline;
    4-amino-trifluoromethoxybenzene;
    4-Trifluoroethoxyaniline;
    AMino TrifluoroMethoxybenzene;

    CAS No. 461-82-5
    Molecular Formula C7H6F3NO
    Molecular Weight 177.12400
    PSA 35.25000
    LogP 2.74860

    Properties

    Appearance & Physical State light yellow liquid
    Density 1.31
    Boiling Point 73-75ºC (10 mmHg)
    Flash Point 80ºC
    Refractive Index 1.462-1.464
    Stability Stable under normal temperatures and pressures.
    Storage Condition Keep away from sources of ignition. Store in a cool, dry place. Store in a tightly closed container.
    Vapor Pressure 2.97mmHg at 25°C

    Safety Info

    Safety Statements S26-S36/37/39
    HS Code 2921420090
    WGK Germany 2
    RIDADR UN 2941
    Risk Statements R20/21/22; R36/37/38
    Hazard Codes Xn

    Synthesis Route

    1-Nitro-4-(trifluoromethoxy)benzene→4-(Trifluoromethoxy)aniline
    1-Bromo-4-(trifluoromethoxy)benzene→4-(Trifluoromethoxy)aniline
    N-2-propynyl-4-(trifluoromethoxy)benzenamine→4-(Trifluoromethoxy)aniline

    Precursor

    4-(trichloromethoxy)benzoyl chloride
    1-Nitro-4-(trifluoromethoxy)benzene
    4-(Trifluoromethoxy)benzamide
    1-Bromo-4-(trifluoromethoxy)benzene

    Downstream Product

    (3S)-4-hydroxy-3-phenyl-6-(trifluoromethoxy)-3H-quinolin-1-ium-2-one
    carbonyl cyanide p-trifluoromethoxyphenylhydrazone
    4-(Trifluoromethoxy)phenyl isocyanate
    3-acetyl-6-(trifluoromethoxy)-1H-benzimidazol-2-one

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