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4-Nitro-2-picoline N-oxide

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Origin: China

Cas No: 5470-66-6

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Quick Details
CAS No.:
5470-66-6
Other Names:
2-Methyl-4-nitropyridine-N-oxide
MF:
C6H6N2O3
EINECS No.:
5470-66-6
Place of Origin:
Anhui, China
Type:
Pharmaceutical Intermediates
Purity:
99%
Brand Name:
GSK
Model Number:
5470-66-6
Application:
Chemical
Appearance:
White Endocardial pocket
CAS:
5470-66-6
MW:
154.12g/mol
Assay:
99%
Grade:
Phamaceutical Grade
Shelf life:
Aluminum foil bag
Storage:
Room Temperature
Packing:
1kg/Alu bag or 25kg/Drum
Brand:
GSK
Origin:
China
Packaging&Delivery
Packaging Details
1kg/Alu bag or 25kg/Drum
Packing method :Woven bag or draft paper bag atteched polyethylene endometrium bag packing tightly or as buyer request
Port
Any Port
Lead Time:
Quantity(Kilograms) 1 - 25 >25
Est. Time(days) 30 To be negotiated

Property

CAS No.: 5470-66-6 Formula: C6H6N2O3 Molecular Weight: 154.12300

Description

A nitroheterocyclic compound and its potential suitability as radiosensitizer for cancer radiotherapy.

Basic Info

Chemical Name	4-Nitro-2-picoline N-oxide
Synonyms	Pyridine, 2-methyl-4-nitro-, 1-oxide; 2-methyl-4-nitro-1-oxidopyridin-1-ium;
CAS No.	5470-66-6
Molecular Formula	C6H6N2O3
Molecular Weight	154.12300
PSA	71.28000
LogP	1.85490

Properties

Appearance & Physical State	powder
Density	1.36 g/cm3
Boiling Point	404ºC at 760 mmHg
Melting Point	155-159ºC
Flash Point	198.1ºC
Storage Condition	2-8ºC

Safety Info

RTECS	UT5710000
Hazard Class	6.1
Safety Statements	S22-S26-S36
HS Code	2933399090
WGK Germany	3
Packing Group	III
RIDADR	UN 2811
Risk Statements	R20/21/22; R36/37/38; R40
Hazard Codes	Xn
Hazard Declaration	H302; H312; H315; H319; H332; H335; H351
Symbol	GHS07, GHS08
Caution Statement	P261; P280; P305 + P351 + P338
Signal Word	Warning

Synthesis Route

2-Picoline-N-oxide→4-Nitro-2-picoline N-oxide
2-methylpyridine→4-Nitro-2-picoline N-oxide
2-Picoline-N-oxide→4-Nitro-2-picoline N-oxide+3-methoxy-2-methyl-6-nitropyridine 1-oxide

Toxicity

Exposure Route	Type of Test	Species Observed	Dose/Duration	Toxic Effects
Subcutaneous	TDLo - Lowest published toxic dose	Rodent - mouse	1800 mg/kg/15W-I	1.Tumorigenic-equivocal tumorigenic agent by RTECS criteria 2.Tumorigenic-tumors at site of application
-	Mutation in microorganisms	-	250 nmol/plate	-
-	Mutation in microorganisms	-	500 umol/L	-

Precursor

2-Picoline-N-oxide
2-methylpyridine

Downstream Product

2-methyl-N-[(2-methyl-1-oxopyridin-1-ium-4-ylidene)amino]-1-oxidopyridin-4-imine
4-Methoxy-2-methylpyridine
4,4'-azo-bis-(2,2'-dimethylpyridine)
4-Amino-2-picoline

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