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4-[2-(5-Chloro-2-methoxybenzamido)ethyl]benzene Sulfonamide

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Origin: China

Cas No: 16673-34-0

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Property

CAS No.: 16673-34-0 Formula: C16H17ClN2O4S Molecular Weight: 368.83500

Description

An impurity arising in the synthesis of Glyburide.

Basic Info

Chemical Name	4-[2-(5-Chloro-2-methoxybenzamido)ethyl]benzene Sulfonamide
Synonyms	5-Chloro-2-methoxy-N-[2-(4-sulfamoylphenyl)ethyl]benzamide; 5-Chloro-2-methoxy-N-(4-sulfamoylphenethyl)benzamide;
CAS No.	16673-34-0
Molecular Formula	C16H17ClN2O4S
Molecular Weight	368.83500
PSA	106.87000
LogP	4.14050

Properties

Appearance & Physical State	Light yellow solid
Density	1.356g/cm3
Melting Point	209-214ºC
Refractive Index	1.597

Safety Info

Safety Statements	S24/25
HS Code	2935009090
WGK Germany	3
Risk Statements	R23/24/25
Hazard Codes	T

Synthesis Route

glibenclamide→4-[2-(5-Chloro-2-methoxybenzamido)ethyl]benzene Sulfonamide+N-Aminopiperidine Hydrochloride
5-CHLORO-2-METHOXYBENZOYL CHLORIDE+4-(2-Aminoethyl)benzenesulfonamide→4-[2-(5-Chloro-2-methoxybenzamido)ethyl]benzene Sulfonamide

Precursor

5-CHLORO-2-METHOXYBENZOYL CHLORIDE
glibenclamide
4-(2-Aminoethyl)benzenesulfonamide

Downstream Product

Ethyl 4-[2-(5-Chloro-2-methoxybenzamido)ethyl]benzene Sulfonamide Carbamate

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