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Home > All categories> Biochemicals and Pharmaceutical Chemicals> Pharmaceutical Impurities> 21-Desacetyl Deflazacort
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21-Desacetyl Deflazacort

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Origin: China

Cas No: 13649-57-5

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 13649-57-5 Formula: C23H29NO5 Molecular Weight: 399.48000

    Description

    A metabolite of Deflazacort, a systemic corticosteroid, a derivative of prednisolone and used for rheumatoid arthritis and lupus.

    Basic Info

    Chemical Name 21-Desacetyl Deflazacort
    Synonyms

    21-DESACETYL DEFLAZACORT;

    CAS No. 13649-57-5
    Molecular Formula C23H29NO5
    Molecular Weight 399.48000
    PSA 96.19000
    LogP 1.42800

    Properties

    Density 1.45g/cm3
    Boiling Point 585ºC at 760mmHg
    Flash Point 307.6ºC
    Refractive Index 1.69

    Synthesis Route

    Deflazacort→21-Desacetyl Deflazacort
    3β-hydroxy-2'-methyl-(5α,16β)-pregn-9(11)-eno[17,16-d]oxazol-20-one→21-Desacetyl Deflazacort
    3β-acetoxy-11β-hydroxy-2'-methyl-(5α,16β)-pregnano[17,16-d]oxazol-20-one→21-Desacetyl Deflazacort

    Precursor

    3β-hydroxy-2'-methyl-(5α,16β)-pregn-9(11)-eno[17,16-d]oxazol-20-one
    Deflazacort
    3β-acetoxy-11β-hydroxy-2'-methyl-(5α,16β)-pregnano[17,16-d]oxazol-20-one
    3β-acetoxy-2'-methyl-(5α,16β)-pregn-9(11)-eno[17,16-d]oxazol-20-one

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