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2-(3-Chloropropyl)-2-(4-fluorophenyl)-1,3-dioxolane

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Origin: China

Cas No: 3308-94-9

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 3308-94-9 Formula: C12H14ClFO2 Molecular Weight: 244.69000

Description

2-(3-Chloropropyl)-2-(4-fluorophenyl)-1,3-dioxolane is used as a reagent to synthesize Piperidine receptor ligands, compounds that have potential antipsychotic activity. 2-(3-Chloropropyl)-2-(4-fluorophenyl)-1,3-dioxolane is also used as a reagent to synthesize Bromoperidol, a neuroleptic drug that is closely related to Haloperidol.

Basic Info

Chemical Name	2-(3-Chloropropyl)-2-(4-fluorophenyl)-1,3-dioxolane
Synonyms
CAS No.	3308-94-9
Molecular Formula	C12H14ClFO2
Molecular Weight	244.69000
PSA	18.46000
LogP	3.04430

Properties

Appearance & Physical State	clear colorless to faint yellow liquid
Density	1.219
Boiling Point	162-166ºC (15 mmHg)
Flash Point	147.4ºC
Refractive Index	1.505-1.5075
Water Solubility	insoluble
Stability	Stable at room temperature in closed containers under normal storage and handling conditions.
Storage Condition	Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Safety Info

Safety Statements	S26-S37/39
HS Code	2932999099
Risk Statements	R36/37/38
Hazard Codes	Xi

Synthesis Route

Ethylene glycol+4-Chloro-4'-fluorobutyrophenone→2-(3-Chloropropyl)-2-(4-fluorophenyl)-1,3-dioxolane
4-Chloro-4'-fluorobutyrophenone→2-(3-Chloropropyl)-2-(4-fluorophenyl)-1,3-dioxolane

Precursor

4-Chloro-4'-fluorobutyrophenone
Ethylene glycol

Downstream Product

1-(4-fluorophenyl)-4-[4-(2-sulfanylidene-3H-benzimidazol-1-yl)piperidin-1-yl]butan-1-one
4-Chloro-4'-fluorobutyrophenone
1-[3-[2-(4-fluorophenyl)-1,3-dioxolan-2-yl]propyl]piperazine
haloperidol

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