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1-(bromomethyl)-3,5-bis(trifluoromethyl)benzene

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Origin: China

Cas No: 32247-96-4

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Quick Details
CAS No.:
32247-96-4
Other Names:
3,5-Bis(trifluoromethyl)benzyl bromide
MF:
C9H5BrF6
EINECS No.:
250-971-1
Place of Origin:
Shandong, China
Type:
Pharmaceutical Intermediates
Purity:
99%MIN
Brand Name:
bosschemical
Model Number:
32247-96-4
Application:
organic intermediates
Appearance:
colorless liquid
Product name:
3,5-Bis(trifluoromethyl)benzyl bromide
Description:
colorless liquid
CAS:
32247-96-4
Synonyms:
3,5-Bis(trifluoromethyl)benzyl bromide
brands:
boss
Assay:
99%min
Package:
25kg/drum
useage:
intermediates
Packaging&Delivery
Packaging Details
5kg/drum, 10kg/drum,25kg/drum,200kg/drum
Port
shanghai, tianjin,qingdao

Property

CAS No.: 32247-96-4 Formula: C9H5BrF6 Molecular Weight: 307.03000

Description

3,5-Bis(trifluoromethyl)benzyl Bromide is used as a reagent in the synthesis of [(chlorophenyl)benzylamino]propanamides as cholesteryl ester transfer protein (CETP) inhibitors. Also used as a reagent in the synthesis of substituted dihydropyridopyrazinedione derivatives as γ-secretase modulators in the treatment of Alzheimer's disease.

Basic Info

Chemical Name	1-(bromomethyl)-3,5-bis(trifluoromethyl)benzene
Synonyms	3,5-di-CF3-benzyl bromide; 1-(Bromomethyl)-3,5-bis(trifluoromethyl)benzene; 3,5-di(trifluoromethyl)benzyl bromide; 1-(bromomethyl)-3,5-di(trifluoromethyl)benzene; 3,5-bis(trifluoromethyl)benzyl bromide; 1,3-bis(trifluoromethyl)-5-(bromomethyl)benzene; 1-Bromomethyl-3,5-bis(trifluoromethyl)benzene;
CAS No.	32247-96-4
Molecular Formula	C9H5BrF6
Molecular Weight	307.03000
PSA	0.00000
LogP	4.61910

Properties

Appearance & Physical State	colorless to yellow brown Clear liquid
Density	1.675
Boiling Point	136-140ºC 14mm
Melting Point	28-30ºC
Flash Point	26ºC
Refractive Index	1.444-1.446
Storage Condition	Flammables area

Safety Info

Hazard Class	8
Safety Statements	S16-S25-S36/37/39-S45
HS Code	2903999090
WGK Germany	3
Packing Group	III
RIDADR	UN 2920
Risk Statements	R10; R34
Hazard Codes	C

Synthesis Route

[3,5-bis(trifluoromethyl)phenyl]methanol→1-(bromomethyl)-3,5-bis(trifluoromethyl)benzene

GC Analysis

Column type	Active phase	Temperature (°C)	Retention Index (I)	Temperature Control Method
Capillary	Polydimethyl siloxanes	-	1103.	custom temperature program

Precursor

[3,5-bis(trifluoromethyl)phenyl]methanol

Downstream Product

1-[[3,5-bis(trifluoromethyl)phenyl]methyl]-3-phenylpiperazine
3-[[3,5-bis(trifluoromethyl)phenyl]methoxy]pyridine
torcetrapib
2,3,3,3-tetrafluoro-2-fluorosulfonylpropanoyl fluoride

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